FASTest® ENCEPH (6 stk.)

Varenummer 825006RK1 Kategorier ,

 

First on-side Antibody Detection – Zoonotic risk Encephalitozoonosis

Beskrivelse

FASTest ENCEPH tester for antistoffer mod Encephalitozoon cuniculi.

E. Cuniculi smitter via meget resistente spore i føde eller fra omgivelser gennem indånding. Testen anvendes som rutinetjek (udelukkelsesdiagnostik) i tilfælde af neurologiske abnormaliteter.

Symptomer på infektion kan være:
– Vestibulært syndrom: Hoved tilt, problemer i bevægelsessystemet, øjenrystelser.
– Tegn på nyresvigt.
– Inflammation i huden omkring øjnene kan forekomme grundet læsioner fra CNS.
– Ufuldstændig lammelse
– Tab af balance
– I sjældne tilfælde kan øget aggression og tab af hørelse eller syn forekomme
– Nyreinsufficiens med uspecifikke symptomer som tab af appetit, vægt, dehydrering, forstyrrelser i mineralbalancen og knoglestofskiftet, samt apati.

Overordnet information om testen:

  • Enkel testprocedure med fuldblod, plasma eller serum.
  • Resultat på kun 10 minutter.
  • Følsomhed: 98,5 % & specificitet: 100 %.
  • Opbevares ved stuetemperatur (15-25 °C).
  • Lang holdbarhed.

Test boks med enten 6 eller 25 tests.

 

 

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One Health – Diagnostics taking responsibility
for human and animal health
Fast test for the qualitative detection of antibodies against
Encephalitozoon cuniculi in whole blood, plasma, or serum of the rabbit
Fast, indirect antibody detection
In case of clinical suspicion
(head tilt, ataxia, seizures,
kidney problems)
Routine check in case of neurological
abnormalities – exclusion diagnostics
Identification of
asymptomatic carriers
(zoonosis)

The infection with Encephalitozoon cuniculi occurs via the extremely resistant spores by contaminated food or inhalation in contaminated surroundings. (Domestic) rabbits are primarily affected. Other strains of the pathogen cause disease in immunocompromised Old World mice and carnivores. Although very rare, it can occur in immunocompromised people (zoonosis).

Neurological symptoms, signs of kidney failure, and eye skin inflammation may occur due to lesions in the central nervous system, kidney and eye. Diseased rabbits can experience one or more of these symptoms. The most common is the so-called vestibular syndrome (head tilt, disorders of movement coordination and eye tremors). Other neurological symptoms can include seizures, incomplete paralysis, and loss of balance. In rare cases, increased aggression and loss of hearing or vision may also occur. In some animals, renal insufficiency with rather unspecific symptoms (loss of appetite or weight, dehydration, disorders of the mineral balance and bone metabolism as well as apathy) can be indicative.

The in vivo diagnosis of encephalitozoonosis in rabbits is problematic because of the large number of animals with chronic, asymptomatic infection. In this case, antibodies can be detected in the blood for years. The serological detection of antibodies against E. cuniculi is therefore considered the safest method, since antibody formation begins 14–28 days after infection. A negative antibody titre after more than 14–28 days excludes an acute infection or a previous contact with E. cuniculi with high probability.

Therefore, the indirect detection of antibodies using FASTest® ENCEPH is of great diagnostic importance (exclusion diagnostics).